HHS Vulnerability Disclosure, Help Is it possible this condition is related to a more serious illness? The rash can appear following sun exposure or from other sources such as tanning beds. In some cases, a doctor might expose a small part of your skin to UV light in order to confirm PMLE. It is rare for people who get sunlight exposure year-round to have PLE. Its the most common skin condition caused by sunlight. Accessed Nov. 12, 2021. Eye. All rights reserved. [1][2], UV-A is theusualpart of the electromagnetic spectrum that provokes polymorphous light eruption (75% to 90%). Our website services, content, and products are for informational purposes only. Polymorphic light eruption is a fairly common skin rash triggered by exposure to sunlight or artificial ultraviolet (UV) light. New insights into the mechanisms of polymorphic light eruption Your healthcare provider can suggest ways to protect your skin from UV light and prevent PMLE. Before According to FDA regulations, sunscreen has a shelf life of 3 years. Some people benefit from phototherapy as a way to harden their skin. The putative antigen induced by UV radiation leads to a predominance of CD4+ T cells and the production of proinflammatory cytokines such as interleukin (IL) 1. (2021). https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun. An official website of the United States government. 2014;23(6):42830. Recently appearing lesions may show neutrophils. 2017 Oct; [PubMed PMID: 28549611], Rizwan M,Reddick CL,Bundy C,Unsworth R,Richards HL,Rhodes LE, Photodermatoses: environmentally induced conditions with high psychological impact. Accessed Dec. 9, 2021. Willan House, 4 Fitzroy Square, London, W1T 5HQ | admin@bad.org.uk | +44 (0)020 7383 0266 However, once the diagnosis is made, the patient may be monitored by the primary care physician and nurse practitioner. Polymorphic light eruption. [6] It is thought to be due to a type IV delayed-type hypersensitivity to an allergen produced in the body following sunlight exposure,[12] in a genetically susceptible person. 2023 Healthline Media UK Ltd, Brighton, UK. 2004 Feb;122(2):291-4. doi: 10.1046/j.0022-202X.2004.22213.x. To reduce the effects of PMLE, the American Academy of Dermatology (AAD) recommends seeking shade and applying sunscreen. Polymorphous light eruption: a common skin disease uncommonly Its diagnosis is based on history, morphology and phototests. (2016). Variegate porphyria[19] and hereditary coproporphyria[20] can also exhibit symptoms of light-induced blisters. Erythema multiforme This generally shows more extensive epidermal necrosis, less spongiosis and the infiltrate often exclusively lymphocytic, Books about skin diseasesBooks about the skin The disorder may be confused with many other skin disorders and thus is best managed by a dermatologist. Theories must account for increased prevalence in women and for the hardening effect of on-going exposure to ultraviolet radiation. It is generally itchy and uncomfortable. Lembo S, et al. A rash can be a symptom of many different conditions. Some people are able to build a tolerance to UV light by gradually spending time outdoors or using phototherapy. 5th ed. Below are some examples of what PMLE can look like. Reactions to physical agents. Polymorphous light eruption(PLE) presents with itchyredsmall bumpson sun-exposed skin, particularly face, neck, forearms and legs.

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