With the practical use of these guidelines, it is expected to reduce the occurrence rate of extravasation and contribute to patient care improvement. Drugs which induce or inhibit hepatic microsomal enzymes may alter diltiazem disposition. For Direct Intravenous Bolus PDF Extravasation Management Reference Sheet - NACNS ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( |a^(/ -~,.[sL5 ;Z]^y~Mq7?7 e GE O G_oiV&! %Lp!8b(V7Yc2|5*qPp4wn"aLKa15N Destroy after 1 month at room temperature. prolonged sedation) of both midazolam and triazolam. If it continues for a long time, the heart and arteries may not function properly. Supplement 5. It is soluble in water, methanol, and chloroform. Diltiazem extravasation. Diltiazem is in a class of medications called calcium-channel blockers. aztreonam, diltiazem hydrochloride, dobutamine hydrochloride, dopamine hydrochloride, fludarabine phosphate, foscarnet sodium, idarubicin hydrochloride, . Data curation: JTK, JYP, HJL, YJC. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Advertising revenue supports our not-for-profit mission. Careers. Cleanse the extravasation site gently with an alcohol sponge, insert the needle of the TB syringe into the subcutaneous tissue around the site and gently aspirate as much of the solution as possible Avoid friction or pressure to the affected area 5. Generic name: diltiazem [dil-TYE-a-zem] This site needs JavaScript to work properly. Stopping suddenly may make your condition worse. DO NOT flush the line 7. This medicine is available only with your doctor's prescription. Soft-tissue disorders | Treatment summaries | BNF | NICE Diltiazem other information we have about you. Sterile eugia 10 x 10 mL Single-Dose Vials, Rx only NDC 55150-427-01 In subgroup analysis of double-blind and open-label trials following first-dose response, 116 patients 65 years of age had a response rate of 84%. Computer-based simulations showed that at a daily dose of 480 mg of diltiazem, an 8- to 9-fold mean increase in simvastatin AUC can be expected. Supplement 3. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. hbbd``b`f3J "-@ ?y "RD%qAaLL )' dJ Treatment suspension wastes time and other problems can occur due to delayed treatment. Drug information: Clinical Computerized Information System: vol. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. For prevention of extravasation, health professionals should be familiar with the extravasation management standard guidelines. Available from: [place unknown]: [publisher unknown]; 2018. The National Extravasation Information Service website [Internet] [cited 2020 Jul 10]. Bethesda, MD 20894, Web Policies HHS Vulnerability Disclosure, Help The audio recording of the abstract. The site is secure. Medically reviewed by Kaci Durbin, MD. Particular information must be given when a vesicant drug is administered. 50 mg per 10 mL We comply with the HONcode standard for trustworthy health information. 0000000956 00000 n However, in rare instances, worsening of congestive heart failure has been reported in patients with preexisting impaired ventricular function. Other prescription and over-the-counter medicines, vitamins, and herbal products may interact with diltiazem. Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. Diltiazem is a calcium channel blocker. At the first sign of extravasation, nursing intervention with following steps is recommended: stop administration of IV fluids immediately, disconnect the IV tube from the cannula, aspirate any remaining drug from the cannula, administer drug-specific antidote, and notify the physician. Seoul: BIT Druginfo; 2020. PDF Diltiazem (Cardizem) - Advocate Health Administration of oral diltiazem in patients with acute myocardial infarction and pulmonary congestion documented by x-ray on admission is contraindicated. 25 mg per 5 mL (5 mg/mL) 5 mL Single-Dose Vials This is an open-access article distributed under the terms of the Creative Commons Attribution License (, GUID:367E9C1D-E270-4114-AA3D-21C537398B1B, GUID:D253D40D-77BC-48AC-A9B8-1814B76155B0, GUID:AD28B884-86A0-4E06-8641-E315D06B067F, GUID:3AC69EF7-5706-454E-AEA5-D87005B23EF4, GUID:D75BDE9D-DD6A-421F-A27E-A2A0FE0A12C1, GUID:6CED1AD4-FC08-4A32-B5E3-E0B71BFF0284, Extravasation, Antidotes, Intravenous injections, Patient care, Risk factors. information highlighted below and resubmit the form. These problems may be less likely to occur if blood pressure is controlled. 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